BDBM50380278 CHEMBL2017246

SMILES CSc1ccccc1Nc1nc(nc2c(NCc3nccs3)ncnc12)N1CCNCC1

InChI Key InChIKey=CRHWNBWMRCMSKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380278   

TargetKetohexokinase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380278(CHEMBL2017246)
Affinity DataIC50:  16nMAssay Description:Inhibition of human ketohexokinase isoform C expressed in Escherichia coli BL21 (DE3) cells using D-fructose as substrate after 12 to 15 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50380278(CHEMBL2017246)
Affinity DataIC50:  270nMAssay Description:Inhibition of ketokinase isoform C in human HepG2 cells assessed as levels of fructose-1-phosphate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed