BDBM50382317 CHEMBL2024684

SMILES Cc1cccc(n1)-n1nccc1-c1ccc2ncn(C)c(=O)c2c1

InChI Key InChIKey=OWIYYKSTVQMPLM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50382317   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)
Affinity DataIC50:  13nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)
Affinity DataIC50:  211nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of ALK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)
Affinity DataIC50:  59nMAssay Description:Inhibition of ALK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed