BDBM50382497 CHEMBL2021950::US10988455, Example 1(xli)

SMILES Cc1cc(cc(C)c1O)-c1nnc(N)nc1-c1ccccc1

InChI Key InChIKey=DSCUJHKNOYFIAC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50382497   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382497(CHEMBL2021950 | US10988455, Example 1(xli))
Affinity DataKi:  2.09nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382497(CHEMBL2021950 | US10988455, Example 1(xli))
Affinity DataKi:  4.07nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382497(CHEMBL2021950 | US10988455, Example 1(xli))
Affinity DataKi:  14.8nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM50382497(CHEMBL2021950 | US10988455, Example 1(xli))
Affinity DataKi:  16.6nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed