BDBM50384698 CHEMBL2037132

SMILES Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(c2)C(F)(F)F)c(=O)c2cnc(CO)cc12

InChI Key InChIKey=RUZAXAPUUTWBTF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384698   

TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384698(CHEMBL2037132)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 G-protein assessed as Ca2+ mobilization after 60 to 90 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384698(CHEMBL2037132)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human S1P1 receptor expressed in human U2OS cells co-expressing eGFP assessed as receptor internalization after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed