BDBM50384721 CHEMBL2037224

SMILES FC(F)(F)c1cccc(NC(=O)Nc2cccc(Nc3ccc4\C(=C\c5ccc[nH]5)C(=O)Nc4c3)c2)c1

InChI Key InChIKey=JCRUDKWPDBIGME-UCQKPKSFSA-N

Data  25 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50384721   

TargetTyrosine-protein kinase receptor Tie-1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Tel-fused ZAP70 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  120nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Tel-fused MET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  130nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Tel-fused FGR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Tel-fused FGFR4 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Tel-fused FGFR3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Tel-fused EPHA3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Tel-fused ALK in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  40nMAssay Description:Inhibition of TRKC by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  7nMAssay Description:Inhibition of TRKA by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384721(CHEMBL2037224)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed