BDBM50385444 CHEMBL2036742

SMILES OC(=O)Cc1cccc(c1)-c1ccc(NC(=O)c2nnc(Nc3ccccc3F)o2)cc1

InChI Key InChIKey=MLUXMNCPCSFOHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385444   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385444(CHEMBL2036742)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed