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BDBM50390674 CHEMBL2070199

SMILES: Clc1cccc(Nc2ncnc3ccc(NCc4ccc5OCCCOc5c4)cc23)c1

InChI Key: InChIKey=YRCJXUNBUGZDOX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390674   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50390674
PNG
(CHEMBL2070199)
Show SMILES Clc1cccc(Nc2ncnc3ccc(NCc4ccc5OCCCOc5c4)cc23)c1
Show InChI InChI=1S/C24H21ClN4O2/c25-17-3-1-4-19(12-17)29-24-20-13-18(6-7-21(20)27-15-28-24)26-14-16-5-8-22-23(11-16)31-10-2-9-30-22/h1,3-8,11-13,15,26H,2,9-10,14H2,(H,27,28,29)
PDB
MMDB

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Article
PubMed
n/an/a 216n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of EGFR in human A431 cell lysate using tyrosine/glutamic acid polymer as substrate by ELISA


Bioorg Med Chem Lett 22: 5870-5 (2012)


Article DOI: 10.1016/j.bmcl.2012.07.079
BindingDB Entry DOI: 10.7270/Q26T0NRG
More data for this
Ligand-Target Pair