BDBM50392279 CHEMBL2153647
SMILES [#8]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1cccc(c1)\[#7]=[#6]-1/[#7]-[#6]-[#6]-[#6]-[#7]-1)-[#7]-[#6](=O)-[#8]-[#6]-c1ccc(cc1)-[#6](-[#8])=O
InChI Key InChIKey=MRXQBHPWVQTUKZ-QHCPKHFHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50392279
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 0.0820nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta3 after 3 hrs by gamma counterMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin expressed in PC3 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin over expressed in A2780 cellsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Sigma-Tau Industrie Farmaceutiche Riunite
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta5 after 3 hrs by gamma counterMore data for this Ligand-Target Pair