BDBM503932 US11034692, Compound 211::cis-N-(8-amino-6-(2,3-dihydro-1H- pyrrolo[2,3-c]pyridin-4-yl)-2,7- naphthyridin-3-yl)-2- fluorocyclopropanecarboxamide

SMILES Nc1nc(cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12)-c1cncc2NCCc12

InChI Key InChIKey=AOMAJCKOWLJRAN-RISCZKNCSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503932   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM503932(US11034692, Compound 211 | cis-N-(8-amino-6-(2,3-d...)
Affinity DataKi:  0.154nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent