BDBM50396076 CHEMBL2170739

SMILES Cc1ccc2c(c1C)n(CCCN)c1ccccc1c2=O

InChI Key InChIKey=CFPDEQBPNROZDC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50396076   

TargetTyrosine-protein kinase SYK(Human)
Rigel

Curated by ChEMBL
LigandPNGBDBM50396076(CHEMBL2170739)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SYK in human mast cells by immunoprecipitation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Rat)
Rigel

Curated by ChEMBL
LigandPNGBDBM50396076(CHEMBL2170739)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells by immunoprecipitation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Rat)
Rigel

Curated by ChEMBL
LigandPNGBDBM50396076(CHEMBL2170739)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated 5-HT releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Rat)
Rigel

Curated by ChEMBL
LigandPNGBDBM50396076(CHEMBL2170739)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated arachidonic acid releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Rat)
Rigel

Curated by ChEMBL
LigandPNGBDBM50396076(CHEMBL2170739)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated inositol phosphate releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Rat)
Rigel

Curated by ChEMBL
LigandPNGBDBM50396076(CHEMBL2170739)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SYK in rat RBL2H3 cells assessed as reduction in DNP-BSA-stimulated Fcepsilon receptor 1-mediated TNFalpha releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed