BDBM50396080 CHEMBL2170754
SMILES Cc1ccc(cc1O)C(=O)c1nc2ccc(O)cc2s1
InChI Key InChIKey=PJRMJIREEYPPSW-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50396080
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human placental cytosolic 17beta HSD1 using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human placenta 17beta-HSD1 cytosolic fraction using unlabelled and [2,4,6,7-3H]estrone as substrate after 10 mins by HPLC analysis in p...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human placenta 17beta-HSD2 microsomal fraction using unlabelled and [2,4,6,7-3H]estradiol as substrate after 20 mins by HPLC analysis i...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using unlabelled and [2,4,6,7-3H]estrone as substrate preincubated for 30 mins prior to substrate addit...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair