BDBM50396245 CHEMBL2172306

SMILES CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(N)=O)cc12

InChI Key InChIKey=JEOWLAWZNDXECM-GUOBSTCESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396245   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396245(CHEMBL2172306)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50396245(CHEMBL2172306)
Affinity DataIC50:  4nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed