BDBM50396845 CHEMBL2170294

SMILES Cc1ccccc1-n1nc(ccc1=O)-c1c2NC[C@@H](CO)Cn2nc1-c1ccc(F)cc1

InChI Key InChIKey=LYHNSWOZRDSWLX-MRXNPFEDSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50396845   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant JNK2alpha2-mediated ATF-2 phosphorylation after 30 mins by immunoblotting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50:  36nMAssay Description:Inhibition of human MAPK p38beta by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50:  11nMAssay Description:Inhibition of human MAPK p38alpha by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG by Rb ion flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50396845(CHEMBL2170294)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed