BDBM50396845 CHEMBL2170294
SMILES Cc1ccccc1-n1nc(ccc1=O)-c1c2NC[C@@H](CO)Cn2nc1-c1ccc(F)cc1
InChI Key InChIKey=LYHNSWOZRDSWLX-MRXNPFEDSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50396845
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant JNK2alpha2-mediated ATF-2 phosphorylation after 30 mins by immunoblotting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human MAPK p38beta by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human MAPK p38alpha by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG by Rb ion flux assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 using midazolam as substrateMore data for this Ligand-Target Pair