BDBM50397735 CHEMBL2181980

SMILES O=C(OCc1ccc(cc1)C#N)[C@H]1C[C@]2(CN1)C(=O)Nc1ccccc21

InChI Key InChIKey=QVGGPTMZUCXDDT-YLJYHZDGSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397735   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397735(CHEMBL2181980)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant BACE1 using NH-SEVNLAAEF-COOH as substrate after 30 mins by NMR analysisMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397735(CHEMBL2181980)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of human recombinant BACE1 using RGLTTRPGSGLTNIKTEEISEVNLDAEFRHDSGA as substrate after 1 hr by TMB-ELISAMore data for this Ligand-Target Pair