BDBM50398252 CHEMBL2177880

SMILES Cc1ncc(CO)c2c(Nc3ccccn3)c(NC[Si](C)(C)C)oc12

InChI Key InChIKey=HNYSVRGKQXKWOY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398252   

TargetToll-like receptor 8(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50398252(CHEMBL2177880)
Affinity DataEC50:  4.99E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by measuring extracellular secreted alkaline pho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed