BDBM50398308 CHEMBL2177331
SMILES COc1ccc2Oc3ccc(cc3C3(COC(N)=N3)c2c1)-c1cc(Cl)ccc1F
InChI Key InChIKey=WIRKEQRUHLXVOQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50398308
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant BACE1 using Glu-Ile-Asp-Leu-Met-Val-Leu-Asp as substrate incubated for 60 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 4.29E+3nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP Swedish mutant assessed as reduction in amyloid beta 40 production after overnight incubatio...More data for this Ligand-Target Pair