BindingDB logo
myBDB logout

BDBM50398731 CHEMBL2179643

SMILES: OC(=O)c1cc(cc(c1)[N+]([O-])=O)-c1cccc(COc2ccc3c(c2)sn(C2CCCC2)c3=O)c1

InChI Key: InChIKey=PZLYFIUJOKQBFD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398731   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50398731
PNG
(CHEMBL2179643)
Show SMILES OC(=O)c1cc(cc(c1)[N+]([O-])=O)-c1cccc(COc2ccc3c(c2)sn(C2CCCC2)c3=O)c1
Show InChI InChI=1S/C26H22N2O6S/c29-25-23-9-8-22(14-24(23)35-27(25)20-6-1-2-7-20)34-15-16-4-3-5-17(10-16)18-11-19(26(30)31)13-21(12-18)28(32)33/h3-5,8-14,20H,1-2,6-7,15H2,(H,30,31)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 200n/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assay


J Med Chem 55: 9434-45 (2012)


Article DOI: 10.1021/jm3005306
BindingDB Entry DOI: 10.7270/Q2RX9D78
More data for this
Ligand-Target Pair