BDBM50398789 CHEMBL2180073

SMILES C[C@@H](N1CC(C1)Oc1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1

InChI Key InChIKey=FHBANDDJQJAZOQ-CQSZACIVSA-N

Data  1 KI  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398789   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50398789(CHEMBL2180073)Copy SMILESCopy InChI

Affinity DataKi:  293nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair

Target InfoNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50398789(CHEMBL2180073)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PDE1CMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50398789(CHEMBL2180073)Copy SMILESCopy InChI

Affinity DataIC50:  22nMAssay Description:Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI