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BDBM50400206 CHEMBL2180993

SMILES: ONC(=O)C(Cc1ccc(F)cc1)C(=O)NCc1ccccc1

InChI Key: InChIKey=UBULRDFJXZRBJH-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400206   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase


(Homo sapiens (Human))
BDBM50400206
PNG
(CHEMBL2180993)
Show SMILES ONC(=O)C(Cc1ccc(F)cc1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C17H17FN2O3/c18-14-8-6-12(7-9-14)10-15(17(22)20-23)16(21)19-11-13-4-2-1-3-5-13/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National Center for Scientific Research Demokritos

Curated by ChEMBL


Assay Description
Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected insect cells using L-arginine-7-amido-4-methylcoumarine as substra...


ACS Med Chem Lett 8: 333-337 (2017)


Article DOI: 10.1021/acsmedchemlett.6b00505
BindingDB Entry DOI: 10.7270/Q26M390J
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50400206
PNG
(CHEMBL2180993)
Show SMILES ONC(=O)C(Cc1ccc(F)cc1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C17H17FN2O3/c18-14-8-6-12(7-9-14)10-15(17(22)20-23)16(21)19-11-13-4-2-1-3-5-13/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 1.32E+3n/an/an/an/an/an/a



University of Lille

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney microsomal neutral aminopeptidase using Leu-pNA as substrate preincubated for 10 mins


J Med Chem 55: 10909-17 (2012)


Article DOI: 10.1021/jm301506h
BindingDB Entry DOI: 10.7270/Q2Z60Q6R
More data for this
Ligand-Target Pair