BDBM50400755 CHEMBL2203563
SMILES COc1cnc(COc2ccc(F)c(F)c2)cc1-c1cc2c(CCNC2=O)[nH]1
InChI Key InChIKey=GMIKNOQZLHKCFH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50400755
Affinity DataIC50: 5nMAssay Description:Inhibition of CK1-gamma 2 using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 32 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 254nMAssay Description:Inhibition of CK1-gamma2 in human RKO cell assessed as inhibition of Wnt3a-induced Wnt signaling treated 1 hr prior to Wnt3a ligand addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of CK1-delta using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 11 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human CK1-gamma2 in HEK293 cells assessed as inhibition of doxcycline-induced LRP6 phosphorylation after 2 hrs by electrochemiluminesce...More data for this Ligand-Target Pair