BDBM50401078 CHEMBL2203708
SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(cc1-c1ccc(F)cc1C)N1CCN(CC1)S(C)(=O)=O
InChI Key InChIKey=LWENKLDZCHEYBQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50401078
Affinity DataKi: 0.400nMAssay Description:Displacement of radioligand [3H]SP from wild type human NK1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]osanetant from wild type human NK3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 123nMAssay Description:Competitive inhibition at wild type human NK3 expressed in HEK293 cells assessed as decrease in [MePhe7]NKB-induced [3H]IP accumulation after 20 minsMore data for this Ligand-Target Pair