BDBM50402386 CHEMBL2207747

SMILES CC(=O)NC1CC2CCC(C1)N2CCc1ccc(Oc2nc3ncccc3s2)cc1

InChI Key InChIKey=KVRXDZGSMIJSDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402386   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50402386(CHEMBL2207747)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant LTA4 hydrolase expressed in SF9 cells using LTA4 as substrate assessed as LTB4 production incubated for 10 mins prior...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50402386(CHEMBL2207747)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50402386(CHEMBL2207747)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of dofetilide binding to human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed