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BDBM50404837 CHEMBL80657

SMILES: CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)CCS

InChI Key: InChIKey=NCQWMIDMMZIYGM-NSHDSACASA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50404837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin-converting enzyme


(Homo sapiens (Human))
BDBM50404837
PNG
(CHEMBL80657)
Show SMILES CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)CCS
Show InChI InChI=1S/C13H17NO3S/c1-14(12(15)7-8-18)11(13(16)17)9-10-5-3-2-4-6-10/h2-6,11,18H,7-9H2,1H3,(H,16,17)/t11-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.09E+4n/an/an/an/an/an/a



Washington University

Curated by ChEMBL


Assay Description
Inhibitory activity against angiotensin converting enzyme (ACE)


J Med Chem 36: 2390-403 (1993)


Article DOI: 10.1021/jm00068a017
BindingDB Entry DOI: 10.7270/Q2Z320V9
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme


(Oryctolagus cuniculus)
BDBM50404837
PNG
(CHEMBL80657)
Show SMILES CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)CCS
Show InChI InChI=1S/C13H17NO3S/c1-14(12(15)7-8-18)11(13(16)17)9-10-5-3-2-4-6-10/h2-6,11,18H,7-9H2,1H3,(H,16,17)/t11-/m0/s1
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Angiotensin I converting enzyme in rabbit lung, using hippuryl-histidyl-leucine as substrate


J Med Chem 25: 250-8 (1982)


Article DOI: 10.1021/jm00345a011
BindingDB Entry DOI: 10.7270/Q28053SJ
More data for this
Ligand-Target Pair