BDBM50405990 CHEMBL19771
SMILES Nc1ncc(Cc2ccc(OC(F)(F)F)cc2)c(N)n1
InChI Key InChIKey=MOQBRTUVUCVOLA-UHFFFAOYSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50405990
Affinity DataKi: 269nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Salmonella enterica subsp. enterica serovar Typhi)
Pomona College
Curated by ChEMBL
Pomona College
Curated by ChEMBL
Affinity DataKi: 269nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Compound is evaluated for the inhibition of dihydrofolate reductase from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 501nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 501nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Lactobacillus casei (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMpH: 7.2Assay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of dihydrofolate reductase from bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.79E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair