BDBM50406891 CHEMBL4163110

SMILES OC(=O)c1nc2ccccc2nc1Nc1ccc(O)cc1

InChI Key InChIKey=OVFXYHHZLWWAJN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50406891   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50:  290nMAssay Description:Inhibition of recombinant human Pim1 expressed in bacterial expression system using histone H1 as substrate after 30 mins by ADP-Glo reagent based lu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50:  98nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain (1 to 499 residues) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK2/CyclinA using histone H1 as substrate after 30 mins by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of porcine brain GSK-3alpha/beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate after 30 mins by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human haspin kinase domain (470 to 798 residues) expressed in bacterial expression system using histone H3 peptide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacterial expression system using GRSRSRSRSRSR as substrate after 30 mins by ADP-Glo reagent based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University Of Tours

Curated by ChEMBL
LigandPNGBDBM50406891(CHEMBL4163110)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CDK9/CyclinT expressed in baculovirus infected Sf9 insect cells using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed