BDBM50408175 CHEMBL410531

SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1

InChI Key InChIKey=BUOWEEIISDGZDM-UHFFFAOYSA-N

Data  6 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50408175   

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Show SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1
Show InChI InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
Affinity DataIC50: 20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor was measured using [3H]granisetron as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Show SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1
Show InChI InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor was measured using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Show SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1
Show InChI InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
Affinity DataIC50: 4.07E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor was measured using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Show SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1
Show InChI InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against 5-Hydroxytryptamine 2C Receptor was measured using [3H]N-methyl-mesulergine as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(BOVINE)
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Show SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1
Show InChI InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor was measured using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Universit£ de Caen

Curated by ChEMBL
LigandPNGBDBM50408175(CHEMBL410531)
Show SMILES Fc1ccc(CN2CCN(CC2)c2nc3cc(Cl)ccc3n3cccc23)cc1
Show InChI InChI=1S/C22H20ClFN4/c23-17-5-8-20-19(14-17)25-22(21-2-1-9-28(20)21)27-12-10-26(11-13-27)15-16-3-6-18(24)7-4-16/h1-9,14H,10-13,15H2
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1B receptor was measured using [3H]5-HT as radioligandMore data for this Ligand-Target Pair