BDBM50415138 CHEMBL576078

SMILES CCCc1ccccc1C(C)OC1=NCCN1

InChI Key InChIKey=CKZOGIXOGHVXNW-UHFFFAOYSA-N

Data  3 KI  2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50415138   

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Universita degli Studi di Camerino

Curated by ChEMBL
LigandPNGBDBM50415138(CHEMBL576078)
Show SMILES CCCc1ccccc1C(C)OC1=NCCN1
Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]RX821002 from human alpha2A adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Universita degli Studi di Camerino

Curated by ChEMBL
LigandPNGBDBM50415138(CHEMBL576078)
Show SMILES CCCc1ccccc1C(C)OC1=NCCN1
Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)
Affinity DataKi:  148nMAssay Description:Displacement of [3H]RX821002 from human Alpha-2C adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Universita degli Studi di Camerino

Curated by ChEMBL
LigandPNGBDBM50415138(CHEMBL576078)
Show SMILES CCCc1ccccc1C(C)OC1=NCCN1
Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)
Affinity DataKi:  537nMAssay Description:Displacement of [3H]RX821002 from human alpha2B adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Universita degli Studi di Camerino

Curated by ChEMBL
LigandPNGBDBM50415138(CHEMBL576078)
Show SMILES CCCc1ccccc1C(C)OC1=NCCN1
Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human alpha2B adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Universita degli Studi di Camerino

Curated by ChEMBL
LigandPNGBDBM50415138(CHEMBL576078)
Show SMILES CCCc1ccccc1C(C)OC1=NCCN1
Show InChI InChI=1S/C14H20N2O/c1-3-6-12-7-4-5-8-13(12)11(2)17-14-15-9-10-16-14/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,15,16)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human Alpha-2C adrenoceptor expressed in CHO cells assessed as extracellular acidification by cytosensor microphysiometryMore data for this Ligand-Target Pair