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BDBM50415763 CHEMBL1081077

SMILES: O=c1c(\C=C\c2ccccc2C#N)c(N2CCN(CC3CCCCC3)CC2)c1=O

InChI Key: InChIKey=KSWHJMMTIWWPIR-ZHACJKMWSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415763   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteinase-activated receptor 1


(Homo sapiens (Human))
BDBM50415763
PNG
(CHEMBL1081077)
Show SMILES O=c1c(\C=C\c2ccccc2C#N)c(N2CCN(CC3CCCCC3)CC2)c1=O
Show InChI InChI=1S/C24H27N3O2/c25-16-20-9-5-4-8-19(20)10-11-21-22(24(29)23(21)28)27-14-12-26(13-15-27)17-18-6-2-1-3-7-18/h4-5,8-11,18H,1-3,6-7,12-15,17H2/b11-10+
PDB

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Article
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n/an/an/a 427n/an/an/an/an/a



Centre de Recherche Pierre Fabre

Curated by ChEMBL


Assay Description
Antagonist activity at PAR1 expressed in CHO cells assessed as inhibition of SFLLR-NH2-induced calcium release by FLIPR assay


Bioorg Med Chem Lett 20: 1735-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.050
BindingDB Entry DOI: 10.7270/Q25M66ZP
More data for this
Ligand-Target Pair