BDBM50416396 CHEMBL1210703

SMILES Cc1ccc(NC(=O)c2cc(c(s2)N2CCOCC2)-c2ccccc2)c(C)c1

InChI Key InChIKey=AJTVQZWUKUPHIP-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416396   

TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human alpha4 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataIC50:  2.51E+3nMAssay Description:Antagonist activity at human alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataEC50:  158nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed