BDBM50416396 CHEMBL1210703
SMILES Cc1ccc(NC(=O)c2cc(c(s2)N2CCOCC2)-c2ccccc2)c(C)c1
InChI Key InChIKey=AJTVQZWUKUPHIP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50416396
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha4 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human 5HT3 receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 158nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair