BDBM504178 N-(6-(4-((5-Ethyl-2-oxo-2,3- dihydrooxazol-4- yl)methyl)piperazin-1-yl)-2,2- dimethyl-2,3- dihydrobenzofuran-5- yl)pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 15

SMILES CCc1oc(=O)[nH]c1CN1CCN(CC1)c1cc2OC(C)(C)Cc2cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=HCZZQCPIXSZTEN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504178   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504178(N-(6-(4-((5-Ethyl-2-oxo-2,3- dihydrooxazol-4- yl)m...)
Affinity DataKi:  9.40nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent