BDBM50417843 CHEMBL1667967

SMILES O=c1[nH]ccc2cc(O[C@H]3CCCNC3)ccc12

InChI Key InChIKey=SNQKPKFVSANKFP-LBPRGKRZSA-N

Data  2 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50417843   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  501nMAssay Description:Inhibition of human PKCmu by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  316nMAssay Description:Inhibition of human PKCdelta by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  61.7nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  661nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  38.9nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  79.4nMAssay Description:Inhibition of human PrkX by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  251nMAssay Description:Inhibition of ROCK1 by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Msd

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)
Affinity DataIC50:  398nMAssay Description:Inhibition of human PKCeta by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed