BDBM50418044 CHEMBL1229508::US10851083, Example 4::US11618744, Example 4

SMILES OC(=O)c1cnn(c1)-c1nc2cc(Cl)c(F)cc2[nH]1

InChI Key InChIKey=VOINEICHGDKMIS-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418044   

TargetEgl nine homolog 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50418044(CHEMBL1229508 | US10851083, Example 4 | US11618744...)
Affinity DataIC50:  79.4nMAssay Description:Inhibition of PHD2More data for this Ligand-Target Pair
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50418044(CHEMBL1229508 | US10851083, Example 4 | US11618744...)
Affinity DataIC50:  200nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50418044(CHEMBL1229508 | US10851083, Example 4 | US11618744...)
Affinity DataIC50:  200nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair