BDBM504202 (R)-N-(6-Methoxy-2,2-dimethyl- 2,3-dihydrobenzofuran-5-yl)-5- (piperidin-3- ylamino)pyrazolo[1,5- a]pyrimidine-3-carboxamide::US11034698, Example 40

SMILES COc1cc2OC(C)(C)Cc2cc1NC(=O)c1cnn2ccc(N[C@@H]3CCCNC3)nc12

InChI Key InChIKey=PBHCARPAFQCVGI-OAHLLOKOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504202   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504202((R)-N-(6-Methoxy-2,2-dimethyl- 2,3-dihydrobenzofur...)
Affinity DataKi:  0.870nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent