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BDBM50423730 CHEMBL594356::NCI-29992

SMILES: COc1cc(NCCCN(CCC(C)C)CCC(C)C)c2ncccc2c1

InChI Key: InChIKey=FQFFHYKRIDVWGP-UHFFFAOYSA-N

Data: 1 IC50

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Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423730   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDK6/cyclin D1


(Homo sapiens (Human))
BDBM50423730
PNG
(CHEMBL594356 | NCI-29992)
Show SMILES COc1cc(NCCCN(CCC(C)C)CCC(C)C)c2ncccc2c1
Show InChI InChI=1S/C23H37N3O/c1-18(2)9-14-26(15-10-19(3)4)13-7-12-24-22-17-21(27-5)16-20-8-6-11-25-23(20)22/h6,8,11,16-19,24H,7,9-10,12-15H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.25E+5n/an/an/an/an/an/a



Veterans Affairs Medical Center

Curated by ChEMBL


Assay Description
Inhibition of CDK6/Cyclin D1 by FRET assay


Bioorg Med Chem Lett 20: 403-5 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.046
BindingDB Entry DOI: 10.7270/Q2GH9K7Q
More data for this
Ligand-Target Pair