BDBM504250 N-(2-((R)-2-Fluoro-3-hydroxy- 3-methylbutyl)-6-((R)- hexahydropyrrolo[1,2- a]pyrazin-2(1H)-yl)-1- oxoisoindolin-5-yl)pyrazolo[1,5- a]pyrimidine-3-carboxamide::US11034698, Example 100

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCN2CCC[C@@H]2C1

InChI Key InChIKey=YNCVICSIPJUZCJ-WZONZLPQSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504250   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504250(N-(2-((R)-2-Fluoro-3-hydroxy- 3-methylbutyl)-6-((R...)
Affinity DataKi:  1.80nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent