BDBM504255 (6S)-3-[2,6-Difluoro-4-[2-(3-pyridyl)ethynyl]phenyl]-1-methyl-spiro[hexahydropyrimidine-6,1′-indane]-2,4-dione::US11034699, Example 3

SMILES CN1C(=O)N(C(=O)C[C@]11CCc2ccccc12)c1c(F)cc(cc1F)C#Cc1cccnc1

InChI Key InChIKey=JQTTVBBQZKSMKH-SANMLTNESA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504255   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM504255((6S)-3-[2,6-Difluoro-4-[2-(3-pyridyl)ethynyl]pheny...)
Affinity DataEC50:  61nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent