BDBM50427369 CHEMBL2326012
SMILES CC(C)[C@@](C)(O)[C@@H]1CN(CCN1)c1ccc(Cl)c(n1)-c1n[nH]c2ncccc12
InChI Key InChIKey=DBENCPRFMOMLTO-MGPUTAFESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50427369
Affinity DataKi: 21nMAssay Description:Inhibition of full-length recombinant PKC theta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 60 mins by scintillation counting analysis...More data for this Ligand-Target Pair
Affinity DataKi: 547nMAssay Description:Inhibition of PKC delta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 15 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 1.24E+3nMAssay Description:Inhibition of PKC alpha (unknown origin) using RRRRRKGSFKRKA as substrate after 15 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of PKC-theta in human PBMC cells assessed as inhibition of IL-2 after 24 hrs by bead-based FLISA assayMore data for this Ligand-Target Pair