BDBM50428067 CL-65336::Cyklokapron::Lysteda::TRANEXAMIC ACID::Trans Amcha

SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O

InChI Key InChIKey=GYDJEQRTZSCIOI-LJGSYFOKSA-N

Data  3 KI  7 IC50  5 Kd

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50428067   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKi:  2.00E+6nMAssay Description:Inhibition of human urokinase-type plasminogen activator using S-2444 as substrateMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKi:  2.50E+7nMAssay Description:Inhibition of plasmin (unknown origin) assessed as reduction in amidolytic activityMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKi:  4.00E+7nMAssay Description:Inhibition of human plasmin assessed as inhibition of amidolysis in presence of fibrinogenMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 1.20E+4nMAssay Description:Binding affinity to human full length Glu-plasminogen in buffer assessed as inhibition of interaction with fibrin preincubated for 15 mins followed b...More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 3.10E+3nMAssay Description:Binding affinity to full length Glu-plasminogen in human plasma assessed as inhibition of interaction with fibrin in presence of tPAMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of plasmin (unknown origin) after 18 hrs by arianor mahogany dye-based fibrin plate assayMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human plasmin assessed as inhibition of fibrinogenolysis in presence of fibrinogenMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human plasmin assessed as inhibition of fibrinolysis in presence of fibrinogenMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of plasminogen/fibrinogen interaction in pooled citrated human platelet-poor plasma assessed as inhibition of lysis of CaCl2/t-PA-induced ...More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human Glu-plasminogen/fibrinogen interaction in HEPES buffer assessed as inhibition of lysis of thrombin-induced clot preincubated for ...More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to plasminogen K1 domain (unknown origin)More data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKd:  7.50E+5nMAssay Description:Binding affinity to human plasma full length Glu-plasminogen by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKd:  3.60E+4nMAssay Description:Binding affinity to human plasma N-terminal truncated Lys-plasminogen by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human plasma full length Glu-plasminogen K1 domain by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50428067(CL-65336 | Cyklokapron | Lysteda | TRANEXAMIC ACID...)
Show SMILES NC[C@H]1CC[C@@H](CC1)C(O)=O
Show InChI InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to human plasma N-terminal truncated Lys-plasminogen K1 domain by surface plasmon resonance analysisMore data for this Ligand-Target Pair