BDBM504288 (4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phenyl]-1,1′-dimethyl-spiro[6,7-dihydro-5H-indazole-4,6′-hexahydropyrimidine]-2′,4′-dione::US11034699, Example 14

SMILES CN1C(=O)N(C(=O)C[C@]11CCCc2c1ccn2C)c1c(F)cc(cc1F)C#Cc1ccccc1

InChI Key InChIKey=RDYFWSWITUAFNE-MHZLTWQESA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504288   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM504288((4S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Affinity DataEC50:  75nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent