BDBM50429614 CHEMBL2334589
SMILES COCCOc1cnc(N)nc1-c1c[nH]c2ccc(cc12)C#CC(C)(C)O
InChI Key InChIKey=ZZIZLABGKZWVAW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50429614
Affinity DataIC50: 20nMAssay Description:Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 processing to NFkappaB2 preincubated for 30 mins before LTalpha/beta2 s...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair