BDBM50431705 ADX48621::CHEMBL2346738::Dipraglurant

SMILES Fc1ccc2nc(CCC#Cc3ccccn3)cn2c1


Data  1 IC50

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431705   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
SK Biopharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50431705(ADX48621 | CHEMBL2346738 | Dipraglurant)
Show SMILES Fc1ccc2nc(CCC#Cc3ccccn3)cn2c1
Show InChI InChI=1S/C16H12FN3/c17-13-8-9-16-19-15(12-20(16)11-13)7-2-1-5-14-6-3-4-10-18-14/h3-4,6,8-12H,2,7H2
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair