BDBM504320 US11040968, Example 002::US11136324, Example 3::WX002
SMILES Cc1cc(F)c(cc1-n1cnc(c1)C1CC1)C(=O)Nc1cccc(n1)-c1nnc2CCCCn12
InChI Key InChIKey=FLPJKFBHZBJFGH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 504320
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group
US Patent
Jiangsu Hansoh Pharmaceutical Group
US Patent
Affinity DataIC50: 13.4nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical Group
US Patent
Jiangsu Hansoh Pharmaceutical Group
US Patent
Affinity DataIC50: 5.60nMAssay Description:Primary reaction buffer solution: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOTreatme...More data for this Ligand-Target Pair