BDBM50432706 CHEMBL2348220

SMILES OC(CNCCNC(=O)Nc1ccc(O)cc1)COc1ccc(OCCOCC2CC2)cc1

InChI Key InChIKey=DDDPQBNOYIRDGL-UHFFFAOYSA-N

Data  4 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50432706   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataKd:  18nMAssay Description:Antagonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataKd:  7.08E+3nMAssay Description:Antagonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataKd:  32nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataKd: >1.00E+4nMAssay Description:Antagonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as inhibition of cimaterol-induced [3H]cAMP accumulation incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataEC50:  9.80nMAssay Description:Partial agonist activity at human beta1 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human beta3 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50432706(CHEMBL2348220)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cells assessed as induction of [3H]cAMP accumulation after 5 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed