BDBM50433822 CHEMBL2382321

SMILES Nc1nc(N)c2cc(Nc3ccc4ccccc4c3)cnc2n1

InChI Key InChIKey=CACNBTSCHPWYIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433822   

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50433822(CHEMBL2382321)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in consumption of NADPH using 18 uM DHFA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50433822(CHEMBL2382321)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed