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BDBM50434005 CHEMBL2381013

SMILES: CC1CCC(C1)n1c(=O)cc(O)n(CCc2cccc(Cl)c2)c1=O

InChI Key: InChIKey=PFQGOWLVONHAOF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434005   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel alpha-1C subunit


(Oryctolagus cuniculus)
BDBM50434005
PNG
(CHEMBL2381013)
Show SMILES CC1CCC(C1)n1c(=O)cc(O)n(CCc2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C18H21ClN2O3/c1-12-5-6-15(9-12)21-17(23)11-16(22)20(18(21)24)8-7-13-3-2-4-14(19)10-13/h2-4,10-12,15,22H,5-9H2,1H3
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+4n/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Antagonist activity at rabbit CaV1.2alpha1C transfected in HEK293 cells by FLIPR assay


J Med Chem 56: 4786-97 (2013)


Article DOI: 10.1021/jm4005048
BindingDB Entry DOI: 10.7270/Q28G8N35
More data for this
Ligand-Target Pair