BDBM50434295 CHEMBL2386353

SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N

InChI Key InChIKey=KIZUBVPJNPVIIN-UHFFFAOYSA-N

Data  1 KI  9 EC50

Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50434295   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataKi:  85nMAssay Description:Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  5.90nMAssay Description:Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization as...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  933nMAssay Description:Agonist activity at C-terminal yellow fluorescent protein-fused human FFA4 receptor transfected in HEK293 cells after 5 mins by BRET assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Mus musculus)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  148nMAssay Description:Agonist activity at mouse FFA1 receptor transfected in human T-REX-293 cells measured for 74 secs by calcium mobilization assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  26nMAssay Description:Agonist activity at C-terminal yellow fluorescent protein-fused human FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assay in presenc...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  23nMAssay Description:Agonist activity at C-terminal yellow fluorescent protein-fused human FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human FFA1 receptor transfected in human 1321N1 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Rattus norvegicus)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50434295(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Affinity DataEC50:  324nMAssay Description:Agonist activity at C-terminal yellow fluorescent protein-fused rat FFA1 receptor transfected in HEK293 cells after 5 mins by BRET assayMore data for this Ligand-Target Pair