BDBM50437391 CHEMBL2408632

SMILES OC(=O)[C@@H]1CC[C@@H](CC1)Oc1ccc(cn1)-c1ccc(cn1)-c1nc2ccc(Cl)cc2[nH]1

InChI Key InChIKey=AVNAVTDFGHCMQE-UJKQEGAGSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50437391   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataKi:  5.39E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human ACAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437391(CHEMBL2408632)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed