BDBM504375 US11040034, Ex. No. 54

SMILES Cc1cc(cnn1)-c1nc2ccc(nc2n1C1CC1)C#N

InChI Key InChIKey=ZZHQOCMWHUKNNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504375   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Phasebio Pharmaceuticals

US Patent
LigandPNGBDBM504375(US11040034, Ex. No. 54)
Affinity DataIC50:  5.50E+3nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Phasebio Pharmaceuticals

US Patent
LigandPNGBDBM504375(US11040034, Ex. No. 54)
Affinity DataIC50:  50nMAssay Description:Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent