BDBM50438712 CHEMBL2414697

SMILES CN(CC(O)=O)C(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCOc2ncnc(N)c2C1=O

InChI Key InChIKey=VUFZJFNCHFIXSW-WKILWMFISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438712   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50438712(CHEMBL2414697)
Affinity DataIC50:  26nMAssay Description:Inhibition of human full length DGAT-1 expressed in insect sf9 cells using [14C]decanoylCoA as substrate after 1.5 hrs by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50438712(CHEMBL2414697)
Affinity DataIC50:  421nMAssay Description:Inhibition of DGAT-1-mediated triglyceride synthesis in human HT-29 cells using [3H]-glycerol as substrate incubated for 1 hr prior to substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed