BDBM50439637 CHEMBL2419601
SMILES CC(C)(C)n1cc2OC3(CCN(CC3)C(=O)c3ccc4[nH]ncc4c3)CC(=O)c2n1
InChI Key InChIKey=MDLAYXJCVDNKAB-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50439637
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of rat recombinant ACC1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair